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Article

Establishment of human embryonic stem cell WAe009-A-88 carrying a long QT syndrome mutation in KCNH2.

Stem cell research - 1 Jul 2022

Wen Hong, Sun Lixiang, Zhong Jiaqi, Wu Fujian

Abstract excerpt

Long-QT syndrome type 2 (LQT2) is a life-threatening Mendelian disease caused by genetic variants in KCNH2. Herein, we generated a human embryonic stem cell line (WAe009-A-88) carrying a LQT2 related mutation in KCNH2, c.1720 A>G. The WAe009-A-88 line maintained stem cell-like morphology, expressed high levels of pluripotent markers, had a normal karyotype, and could differentiate into all three germ layers in...

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Identifiers

PMID: 35526388
DOI: 10.1016/j.scr.2022.102795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Establishment of human embryonic stem cell WAe009-A-88 carrying a long QT syndrome mutation in KCNH2.PMID 35526388Read ↗

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