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Article

The generation of induced pluripotent stem cells from a patient with KCNH2 G603D, without LQT2 disease associated symptom.

Journal of medical and dental sciences - 1 Mar 2013

Okata Shinichiro, Yuasa Shinsuke, Yamane Teiichi, Furukawa Tetsushi, Fukuda Keiichi

Abstract excerpt

The long QT syndrome type 2 (LQT2) is inheritable life threatening arrhythmic disorder and one of the most common genetic variants in long QT syndrome. There are some indications for treatment of the patients with LQT2 but it is impossible to completely prevent fatal arrhythmia. To develop novel therapy for the patients with LQT2, it has been desired to generate diseasespecific and patient-specific disease model....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23917959

Genes

KCNH2
NANOG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The generation of induced pluripotent stem cells from a patient with KCNH2 G603D, without LQT2 disease associated symptom.PMID 23917959Read ↗

Establishment of a human-induced pluripotent stem cell line from a long QT syndrome type 2 patient harboring a KCNH2 mutation.Semantic proximity Read ↗

Generation of patient-specific induced pluripotent stem cell lines with Type 2 Long QT Syndrome and the KCNH2 c.379C > T pathogenic variant.Semantic proximity Read ↗

Generation of three heterozygous KCNH2 mutation-carrying human induced pluripotent stem cell lines for modeling LQT2 syndrome.Semantic proximity Read ↗

Generation of an induced pluripotent stem cell line from a long QT syndrome patient carrying KCNH2/1956C > A mutation.Semantic proximity Read ↗

Derivation and characterization of two human induced pluripotent stem cell lines (NUIGi004-A) and (NUIGi012-A) from two patients with LQT2 disease.Semantic proximity Read ↗

Human induced pluripotent stem cell line ZZUNEUi027-A generated from a long QT syndrome patient with a heterozygous KCNH2 (c. 128 A > G) mutant.Semantic proximity Read ↗

Establishment of human embryonic stem cell WAe009-A-88 carrying a long QT syndrome mutation in KCNH2.Semantic proximity Read ↗

Generation of induced pluripotent stem cells (iPSCs) from a Chinese infant (XACHi015-A) with type 2 Long QT syndrome carrying the heterozygous mutation c.1814C>T(p.P605L) in KCNH2.Semantic proximity Read ↗

Generation and characterization of an induced pluripotent stem cell (iPSC) line (NUIGi003-A) from a long QT syndrome type 2 (LQT2) patient harbouring the KCNH2 c.2464G>A pathogenic variant.Semantic proximity Read ↗

Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome.Semantic proximity Read ↗

Generation of a human embryonic stem cell line (WAe009-A-43) carrying a Long QT syndrome related mutation in KCNH2 gene.Semantic proximity Read ↗

Generation of human induced pluripotent stem cell line from a patient with a long QT syndrome type 2.Semantic proximity Read ↗

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