Article
Systematic identification and characterization of genes in the regulation and biogenesis of photosynthetic machinery.
Cell - 7 Dec 2023
Kafri Moshe, Patena Weronika, Martin Lance, Wang Lianyong, Gomer Gillian, Ergun Sabrina L, Sirkejyan Arthur K, Goh Audrey, Wilson Alexandra T, Gavrilenko Sophia E, Breker Michal, Roichman Asael, McWhite Claire D, Rabinowitz Joshua D, Cross Frederick R, Wühr Martin, Jonikas Martin C
Abstract excerpt
Photosynthesis is central to food production and the Earth's biogeochemistry, yet the molecular basis for its regulation remains poorly understood. Here, using high-throughput genetics in the model eukaryotic alga Chlamydomonas reinhardtii, we identify with high confidence (false discovery rate [FDR] < 0.11) 70 poorly characterized genes required for photosynthesis. We then enable the functional characterization...
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