Article
Laryngotracheal Resection After B-Raf Proto-oncogene Inhibition for Anaplastic Thyroid Carcinoma.
The Annals of thoracic surgery - 1 May 2023
Kent Johnathan, Erwin Philip, Haraf Daniel, Liao Chih-Yi, Durham Joseph, Angelos Peter, Agrawal Nishant, Baird Brandon Jackson, Madariaga Maria Lucia L
Abstract excerpt
Anaplastic thyroid carcinoma is a rare but aggressive neoplasm that often presents as advanced inoperable disease. Patients with B-Raf proto-oncogene (BRAF) v600e mutated anaplastic thyroid carcinoma who receive neoadjuvant dabrafenib/trametinib have improved rates of microscopically margin-negative resection and durable locoregional control. However this has not been evaluated in the setting of tracheal...
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