Article
Promising Therapeutic Targets for Recurrent/Metastatic Anaplastic Thyroid Cancer.
Current treatment options in oncology - 1 Jul 2024
Abdalla Abdelrahman Sherif, Rahman Mobeen, Khan Saad A
Abstract excerpt
OPINION STATEMENT: Anaplastic thyroid cancer presents formidable challenges, particularly in cases of recurrence or metastasis. Timely BRAF V600E testing is imperative at diagnosis, initially through immunohistochemistry, followed by comprehensive genomic profiling encompassing genes such as NTRK, RET, ALK, and assessment of tumor mutation burden (TMB). FDA-approved treatment options include dabrafenib and...
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