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Article

Spectrum of Clinical Manifestations in Children With WT1 Mutation: Case Series and Literature Review

15 Apr 2022

Abstract excerpt

Background Mutations of the Wilms tumor suppressor-1 gene (WT1) are associated with life-threatening glomerulopathy, disorders of sexual development, Wilm's tumor, and gonadal malignancies. Our objectives were to describe the clinical presentations, age of progression, and onset of complications of WT1 mutation through a case series and literature review. Methods A retrospective study included all patients...

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Identifiers

PMID: 35498778
DOI: 10.3389/fped.2022.847295

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