Article
Membranoproliferative glomerulonephritis associated with a mutation in Wilms' tumour suppressor gene 1.
Pediatric nephrology (Berlin, Germany) - 1 Jul 2009
Bockenhauer Detlef, van't Hoff William, Chernin Gil, Heeringa Saskia F, Sebire Neil J
Abstract excerpt
Wilms' tumour suppressor gene 1 (WT1) encodes a transcription factor required for normal development of the genitourinary system. In the kidney, mutations in WT1 can cause diffuse mesangial sclerosis or focal segmental glomerulosclerosis. Here, we report on a girl with a mutation in WT1, who deve...
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