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Article

Markers of kidney function, genetic variation related to cognitive function, and cognitive performance in the UK Biobank.

BMC nephrology - 27 Apr 2022

Richard Erin L, McEvoy Linda K, Deary Ian J, Davies Gail, Cao Steven Y, Oren Eyal, Alcaraz John E, LaCroix Andrea Z, Bressler Jan, Salem Rany M

Abstract excerpt

BACKGROUND: Chronic kidney disease has been linked to worse cognition. However, this association may be dependent on the marker of kidney function used, and studies assessing modification by genetics are lacking. This study examined associations between multiple measures of kidney function and assessed effect modification by a polygenic score for general cognitive function. METHODS: In this cross-sectional study...

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Identifiers

PMID: 35477353
DOI: 10.1186/s12882-022-02750-6
PMCID: PMC9047316

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