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Article

Genetic overlap and causal inferences between kidney function and cerebrovascular disease.

Neurology - 16 Jun 2020

Marini Sandro, Georgakis Marios K, Chung Jaeyoon, Henry Jonathan Q A, Dichgans Martin, Rosand Jonathan, Malik Rainer, Anderson Christopher D

Abstract excerpt

OBJECTIVE: Leveraging large-scale genetic data, we aimed to identify shared pathogenic mechanisms and causal relationships between impaired kidney function and cerebrovascular disease phenotypes. METHODS: We used summary statistics from genome-wide association studies (GWAS) of kidney function traits (chronic kidney disease diagnosis, estimated glomerular filtration rate [eGFR], and urinary albumin-to-creatinine...

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Share to Cerebral Small Vessel Diseases
Share to Cerebrovascular Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerular Filtration Rate

Share to Kidney

Share to Kidney Function Tests

Share to Multifactorial Inheritance

Share to Renal Insufficiency, Chronic

Share to Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 32439819
DOI: 10.1212/WNL.0000000000009642
PMCID: PMC7455337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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