Article
Compositionally Aware Phylogenetic Beta-Diversity Measures Better Resolve Microbiomes Associated with Phenotype.
mSystems - 28 Jun 2022
Martino Cameron, McDonald Daniel, Cantrell Kalen, Dilmore Amanda Hazel, Vázquez-Baeza Yoshiki, Shenhav Liat, Shaffer Justin P, Rahman Gibraan, Armstrong George, Allaband Celeste, Song Se Jin, Knight Rob
Abstract excerpt
Microbiome data have several specific characteristics (sparsity and compositionality) that introduce challenges in data analysis. The integration of prior information regarding the data structure, such as phylogenetic structure and repeated-measure study designs, into analysis, is an effective approach for revealing robust patterns in microbiome data. Past methods have addressed some but not all of these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.