Article
The association between FOXO3a rs4946936 gene polymorphism and the levels of FOXO3a among chronic granulocytic leukemia patients treated with imatinib mesylate.
F1000Research - 1 Jan 2021
Wardhani Shinta Oktya, Susianti Hani, Rahayu Puji, Yueniwati Yuyun Prabowowati, Fajar Jonny Karunia
Abstract excerpt
Background:The gene FOXO3a has been elucidated to govern the development of chronic granulocytic leukemia (CGL). Moreover, it has been suggested that the levels of FOXO3a in circulation are affected by the FOXO3a rs4946936 gene polymorphism. However, no study has assessed the correlation between the FOXO3a rs4946936 gene polymorphism and the levels of FOXO3a. The objective of this study was to assess the...
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