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Article

Parkin as a Molecular Bridge Linking Alzheimer’s and Parkinson’s Diseases?

9 Apr 2022

Abstract excerpt

Alzheimer's (AD) and Parkinson's (PD) diseases are two distinct age-related pathologies that are characterized by various common dysfunctions. They are referred to as proteinopathies characterized by ubiquitinated protein accumulation and aggregation. This accumulation is mainly due to altered lysosomal and proteasomal clearing processes and is generally accompanied by ER stress disturbance, autophagic and...

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PMID: 35454148
DOI: 10.3390/biom12040559

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