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Transplacental Zika virus transmission in ex vivo perfused human placentas

20 Apr 2022

Abstract excerpt

A Zika virus (ZIKV) infection during pregnancy can result in severe birth defects such as microcephaly. To date, it is incompletely understood how ZIKV can cross the human placenta. Furthermore, results from studies in pregnant mice and non-human primates are conflicting regarding the role of cross-reactive dengue virus (DENV) antibodies on transplacental ZIKV transmission. Elucidating how ZIKV can cross the...

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PMID: 35442976
DOI: 10.1371/journal.pntd.0010359

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