Article
Current prices versus minimum costs of production for CFTR modulators.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Sept 2022
Guo Jonathan, Wang Junzheng, Zhang Jingchun, Fortunak Joseph, Hill Andrew
Abstract excerpt
BACKGROUND: While the clinical benefits of CFTR modulators are clear, their high prices render them inaccessible outside of the world's richest countries. Despite this, there is currently limited evidence regarding global access to these transformative therapies. Therefore, this study aims to estimate the minimum costs of production of CFTR modulators, assuming robust generic competition, and to compare them with...
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