Article
Urinary CC16, a potential indicator of lung integrity and inflammation, increases in children after short-term exposure to PM2.5/PM10 and is driven by the CC16 38GG genotype.
Environmental research - 1 Sept 2022
Nauwelaerts Sarah J D, Van Goethem Nina, Ureña Berta Tenas, De Cremer Koen, Bernard Alfred, Saenen Nelly D, Nawrot Tim S, Roosens Nancy H C, De Keersmaecker Sigrid C J
Abstract excerpt
Particular matter (PM) exposure is a big hazard for public health, especially for children. Serum CC16 is a well-known biomarker of respiratory health. Urinary CC16 (U-CC16) can be a noninvasive alternative, albeit requiring adequate adjustment for renal handling. Moreover, the SNP CC16 G38A influences CC16 levels. This study aimed to monitor the effect of short-term PM exposure on CC16 levels, measured...
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