Article
Variants in CCL16 are associated with blood plasma and cerebrospinal fluid CCL16 protein levels.
BMC genomics - 29 Jun 2016
Ebbert Mark T W, Staley Lyndsay A, Parker Joshua, Parker Sheradyn, Bailey Matthew, Ridge Perry G, Goate Alison M, Kauwe John S K
Abstract excerpt
BACKGROUND: CCL16 is a chemokine predominantly expressed in the liver, but is also found in the blood and brain, and is known to play important roles in immune response and angiogenesis. Little is known about the gene's regulation. METHODS: Here, we test for potential causal SNPs that affect CCL16 protein levels in both blood plasma and cerebrospinal fluid in a genome-wide association study across two datasets....
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