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Oral Elesclomol Treatment Alleviates Copper Deficiency in Animal Models

1 Apr 2022

Abstract excerpt

Copper (Cu) is an essential trace element for key biochemical reactions. Dietary or genetic copper deficiencies are associated with anemia, cardiomyopathy, and neurodegeneration. The essential requirement for copper in humans is illustrated by Menkes disease, a fatal neurodegenerative disorder of early childhood caused by mutations in the ATP7A copper transporter. Recent groundbreaking studies have demonstrated...

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PMID: 35433682
DOI: 10.3389/fcell.2022.856300

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