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B-Cell Epitope Mapping of TprC and TprD Variants of Treponema pallidum Subspecies Informs Vaccine Development for Human Treponematoses

29 Mar 2022

Abstract excerpt

Several recent studies have focused on the identification, functional analysis, and structural characterization of outer membrane proteins (OMPs) ofTreponema pallidum(Tp). TheTpspecies encompasses the highly relatedpallidum,pertenue, andendemicumsubspecies of this pathogen, known to be the causative agents of syphilis, yaws, and bejel, respectively. These studies highlighted the importance of identifying...

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PMID: 35422800
DOI: 10.3389/fimmu.2022.862491

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