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Article

Case-Control Genotyping of the c.788C>T Variant of Transforming Growth Factor-Beta 1 Gene in Otosclerosis in the South Indian Population.

The journal of international advanced otology - 1 Mar 2022

Kale Deepa, Rekha Santhanam, Vinoth Sigamani, Ramalingam Ravi, Parani Madasamy

Abstract excerpt

BACKGROUND: Otosclerosis is a common conductive hearing loss resulting from abnormal bone metabolism. The c.788C>T variant in the transforming growth factor-beta 1 gene is associated with otosclerosis in all studied populations, except the Indian population. In this study, we predicted the functional effects of reported variants in transforming growth factor-beta 1 and analyzed the c.788C>T variant in a...

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Source

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Identifiers

PMID: 35418358
DOI: 10.5152/iao.2022.21170
PMCID: PMC9450088

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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