Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temporal Control of the WNT Signaling Pathway During Cardiac Differentiation Impacts Upon the Maturation State of Human Pluripotent Stem Cell Derived Cardiomyocytes

24 Mar 2022

Abstract excerpt

Inefficient differentiation and insufficient maturation are barriers to the application of human pluripotent stem cell (hPSC)-derived cardiomyocytes (CMs) for research and therapy. Great strides have been made to the former, and multiple groups have reported cardiac differentiation protocol that can generate hPSC-CMs at high efficiency. Although many such protocols are based on the modulation of the WNT signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35402504
DOI: 10.3389/fmolb.2022.714008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temporal Control of the WNT Signaling Pathway During Cardiac Differentiation Impacts Upon the Maturation State of Human Pluripotent Stem Cell Derived CardiomyocytesPMID 35402504Read ↗

Current methods for the maturation of induced pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cellsSemantic proximity Read ↗

Recent advances in regulating the proliferation or maturation of human-induced pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D CultureSemantic proximity Read ↗

Deciphering Role of Wnt Signalling in Cardiac Mesoderm and Cardiomyocyte Differentiation from Human iPSCs: Four-dimensional control of Wnt pathway for hiPSC-CMs differentiationSemantic proximity Read ↗

Metabolic Maturation in hiPSC-Derived Cardiomyocytes: Emerging Strategies for Inducing the Adult Cardiac PhenotypeSemantic proximity Read ↗

Defined MicroRNAs Induce Aspects of Maturation in Mouse and Human Embryonic-Stem-Cell-Derived CardiomyocytesSemantic proximity Read ↗

Advancements in cardiac regenerative therapy: Scalable human iPSC-derived cardiomyocyte differentiation and maturationSemantic proximity Read ↗

Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturationSemantic proximity Read ↗

Cardiomyocyte Maturation-the Road is not Obstructed.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.