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Article

Non-structural protein 1 (NS1) variants from dengue virus clinical samples revealed mutations that influence NS1 production and secretion.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 May 2022

Ghosh Anisa, Sukla Soumi, Nath Himadri, Saha Rajdeep, De Abhishek, Biswas Subhajit

Abstract excerpt

Dengue diagnosis primarily relies on NS1 ELISA and serological (IgG/IgM) tests. There are reports of low and variable sensitivity of the widely used NS1 ELISA tests. Poor sensitivity has been attributed to patient's infection status, prevalent serotypes, and the geographical origin of the samples. We investigated whether NS1 mutations directly have any impact on NS1 ELISA-based dengue virus (DENV) detection in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35397074
DOI: 10.1007/s10096-022-04441-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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