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Structural biology of flavivirus NS1 protein and its antibody complexes

20 May 2024

Abstract excerpt

The genus of flavivirus includes many mosquito-borne human pathogens, such as Zika (ZIKV) and the four serotypes of dengue (DENV1-4) viruses, that affect billions of people as evidenced by epidemics and endemicity in many countries and regions in the world. Among the 10 viral proteins encoded by the viral genome, the nonstructural protein 1 (NS1) is the only secreted protein and has been used as a diagnostic...

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Identifiers

PMID: 38777094
DOI: 10.1016/j.antiviral.2024.105915

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