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Article

Alcohol and calorie-dense diets modulate immune phenotype and metabolic health in simian immunodeficiency virus infection.

Function (Oxford, England) - 1 Aug 2026

Simon Liz, Mire Megan, McTernan Patrick M, Gallegos Eden M, Coleman Larry, Siggins Robert W, Caro Adam C, Baker Carol L, Molina Patricia E

Abstract excerpt

Alcohol misuse and calorie-dense diets, especially those rich in sugar and fat, independently increase comorbidity risk among people with HIV. The objective of this study was to define the combined effects of chronic binge alcohol administration and consumption of a high-fat high-sucrose diet (HFSD) on systemic metabolic, immunologic, and body composition outcomes under controlled conditions in an established...

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Identifiers

PMID: 42448343
DOI: 10.1152/function.033.2026
PMCID: PMC13460388

Genes

CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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