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Identifying the Effect of Celastrol Against Ovarian Cancer With Network Pharmacology and In Vitro Experiments

18 Mar 2022

Abstract excerpt

Aim: We aimed to reveal the function of celastrol in the treatment of ovarian cancer using network pharmacology and molecular docking. Background: Ovarian cancer is a growth of cells that forms in the ovaries. Celastrol is a useful bioactive compound derived from the root of the thunder god vine. Method: Celastrol and ovarian cancer targets were determined by analyzing datasets. Protein–protein interaction (PPI)...

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PMID: 35370699
DOI: 10.3389/fphar.2022.739478

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