Article
TCGA molecular classification in endometriosis-associated ovarian carcinomas: Novel data on clear cell carcinoma.
Gynecologic oncology - 1 Jun 2022
Similä-Maarala Jonna, Soovares Piret, Pasanen Annukka, Ahvenainen Terhi, Vahteristo Pia, Bützow Ralf, Lassus Heini
Abstract excerpt
BACKGROUND: Clear cell and endometrioid ovarian carcinomas (OCC and OEC, respectively) have a presumed origin in endometriosis and share molecular alterations with each other and with their endometrial counterparts. The Cancer Genome Atlas (TCGA)-based molecular classification stratifies endometrial carcinomas into four categories: POLE mutated (POLEmut), mismatch repair deficient (MMRd), p53 abnormal (p53abn)...
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