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Crosstalk Between ROS and Autophagy in Tumorigenesis: Understanding the Multifaceted Paradox

10 Mar 2022

Abstract excerpt

Cancer formation is a highly regulated and complex process, largely dependent on its microenvironment. This complexity highlights the need for developing novel target-based therapies depending on cancer phenotype and genotype. Autophagy, a catabolic process, removes damaged and defective cellular materials through lysosomes. It is activated in response to stress conditions such as nutrient deprivation, hypoxia,...

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PMID: 35359388
DOI: 10.3389/fonc.2022.852424

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