Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Staphylococcus aureus Multiplexes Death-Effector Deoxyribonucleosides to Neutralize Phagocytes

10 Mar 2022

Abstract excerpt

Adenosine synthase A (AdsA) is a key virulence factor of Staphylococcus aureus, a dangerous microbe that causes fatal diseases in humans. Together with staphylococcal nuclease, AdsA generates deoxyadenosine (dAdo) from neutrophil extracellular DNA traps thereby igniting caspase-3-dependent cell death in host immune cells that aim at penetrating infectious foci. Powered by a multi-technological approach, we here...

Source

Identifiers

PMID: 35355997
DOI: 10.3389/fimmu.2022.847171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Staphylococcus aureus Multiplexes Death-Effector Deoxyribonucleosides to Neutralize PhagocytesPMID 35355997Read ↗

<i>Staphylococcus aureus</i> targets the purine salvage pathway to kill phagocytesSemantic proximity Read ↗

Methicillin-resistant Staphylococcus pseudintermedius synthesizes deoxyadenosine to cause persistent infectionSemantic proximity Read ↗

<i>Staphylococcus aureus nt</i> 5 gene contributes to bacterial infection ability to form kidney abscessSemantic proximity Read ↗

A miniature CRISPR-Cas10 enzyme confers immunity by an inverse signaling pathwaySemantic proximity Read ↗

Streptococcus suis 5’-nucleotidases contribute to adenosine-mediated immune evasion and virulence in a mouse modelSemantic proximity Read ↗

A type III-A CRISPR-Cas system employs degradosome nucleases to ensure robust immunitySemantic proximity Read ↗

Intracellular Staphylococcus aureus and host cell death pathwaysSemantic proximity Read ↗

Streptococcal 5′-Nucleotidase A (S5nA), a Novel Streptococcus pyogenes Virulence Factor That Facilitates Immune EvasionSemantic proximity Read ↗

SSR42 is a Novel Regulator of Cytolytic Activity in <i>Staphylococcus aureus</i>Semantic proximity Read ↗

Cleavage of the catalytic intermediate fine-tunes cGAS signallingSemantic proximity Read ↗

Uncovering novel endolysins against methicillin-resistant <i>Staphylococcus aureus</i> using microbial single-cell genome sequencingSemantic proximity Read ↗

Intracellular staphylococcus aureus: Live-in and let dieSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.