Article
An inactivating mutation in the vacuolar arginine exporter gene Vae results in culture degeneration in the fungus Metarhizium robertsii.
Environmental microbiology - 1 Jul 2022
Song Hui, Bao Yuting, Zhang Mingxiang, Liu Shuxing, Yu Chaonan, Dai Jin, Wu Congcong, Tang Dan, Fang Weiguo
Abstract excerpt
Culture degeneration usually results in great commercial losses in the economically important filamentous fungi, but the genetic causes of the degeneration remain elusive. In the fungus Metarhizium robertsii, we found that deletion of the vacuolar arginine exporter gene Vae caused culture degeneration. Compared to the WT strain, the mutant showed increased apoptosis, reactive oxygen species (ROS) level and...
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