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Whole exome sequencing of pediatric leukemia reveals a novel InDel within FLT-3 gene in AML patient from Mizo tribal population, Northeast India.

BMC genomic data - 28 Mar 2022

Vanlallawma Andrew, Lallawmzuali Doris, Pautu Jeremy L, Scaria Vinod, Sivasubbu Sridhar, Kumar Nachimuthu Senthil

Abstract excerpt

BACKGROUND: Leukemia is the most common type of cancer in pediatrics. Genomic mutations contribute towards the molecular mechanism of disease progression and also helps in diagnosis and prognosis. This is the first scientific mutational exploration in whole exome of pediatric leukemia patients from a cancer prone endogamous Mizo tribal population, Northeast India. RESULT: Three non-synonymous exonic variants in...

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Identifiers

PMID: 35350997
DOI: 10.1186/s12863-022-01037-x
PMCID: PMC8961913

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