Article
Phenotype of limited cutaneous systemic sclerosis patients with positive anti-topoisomerase I antibodies: data from the EUSTAR cohort.
Rheumatology (Oxford, England) - 28 Nov 2022
Zanatta Elisabetta, Huscher Dörte, Ortolan Augusta, Avouac Jérôme, Airò Paolo, Balbir-Gurman Alexandra, Siegert Elise, Matucci Cerinic Marco, Cozzi Franco, Riemekasten Gabriela, Hoffmann-Vold Anna-Maria, Distler Oliver, Gabrielli Armando, Heitmann Stefan, Hunzelmann Nicolas, Montecucco Carlomaurizio, Morovic-Vergles Jadranka, Ribi Camillo, Doria Andrea, Allanore Yannick
Abstract excerpt
OBJECTIVES: To characterize patients with positive anti-topoisomerase I (ATA) in lcSSc. METHODS: SSc patients enrolled in the EUSTAR cohort with a disease duration of ≤3 years at database entry were considered. We assessed the risk of major organ involvement in the following groups: ATA-lcSSc vs ACA-lcSSc and vs ANA without specificity (ANA)-lcSSc, and ATA-lcSSc vs ATA-dcSSc. Cox regression models with...
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