Impact of SARS-CoV-2 Variants on the Analytical Sensitivity of rRT-PCR Assays

Abstract excerpt

= 0.019). The Alpha and Omicron variants had no significant effect on the kits. This study highlights the necessity of identifying the potential effect of viral mutations on the efficacy and sensitivity of clinical detection assays. It can also provide helpful insights regarding the development and optimization of diagnostic assays and aid the strategic management of the ongoing pandemic.

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