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Associations of Maternal rs1801131 Genotype in MTHFR and Serum Folate and Vitamin B12 with Gestational Diabetes Mellitus in Chinese Pregnant Women.

Nutrients - 10 Mar 2022

Li Shuying, Tian Xiubiao, Wang Yiyun, Zhang Xumei, Zhang Liwen, Li Chen, Li Jing, Wang Chunhua, Liu Huihuan, Liu Juan, Liu Hongjuan, Yang Xueli, Li Weiqin, Leng Junhong, Yang Xilin, Tang Naijun, Zhang Qiang

Abstract excerpt

Circumstantial evidence links one-carbon metabolism (OCM) related nutrients, such as folate and vitamin B12, with gestational diabetes mellitus (GDM). However, few studies have evaluated the combined effects of these nutrients with OCM related gene polymorphisms on GDM. This study investigated whether OCM related genetic variants modified the associations of folate and B12 with GDM. Logistic regression was used...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35334827
DOI: 10.3390/nu14061169
PMCID: PMC8954918

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