Article
Associations of MTHFR Polymorphisms and Cytosine Modifications with Early-Gestational Diabetes Mellitus in Chinese Pregnant Women.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Oct 2023
Liu Huan-Yu, Qin Shanshan, Zhang Zhou, Qi Jiahui, Zhang Wei, Liu Song-Mei, Zhang Yuanzhen
Abstract excerpt
Early-Gestational Diabetes Mellitus (Early-GDM) is a complex condition that may cause complications in infants of affected mothers. The aim of this case-control study was to analyze the effects of genetic-epigenetic interaction on Early-GDM and fetal development with respect to cytosine modifications (i.e., 5mC, 5-methylcytosines; and 5hmC, 5-hydroxymethylcytosines) and single nucleotide polymorphisms (SNPs) of...
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