Article
Hereditary renal cell carcinoma: genetics, clinical features, and surgical considerations.
World journal of urology - 1 Jun 2014
Byler Timothy K, Bratslavsky Gennady
Abstract excerpt
OBJECTIVES: Hereditary renal cancer syndromes have been described and have illuminated novel methods to treat sporadic renal cell carcinoma. In this work, we aimed to review the genetic basis, molecular pathology and clinical manifestations of hereditary syndromes, as well as outline principles of surgical management and use of targeted therapy. METHODS: We performed a comprehensive review of selected...
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