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Clinical progress of nanomedicine-based RNA therapies

22 Oct 2021

Abstract excerpt

The clinical application of nanoparticles (NPs) to deliver RNA for therapy has progressed rapidly since the FDA approval of Onpattro® in 2018 for the treatment of polyneuropathy associated with hereditary transthyretin amyloidosis. The emergency use authorization or approval and widespread global use of two mRNA-NP based vaccines developed by Moderna Therapeutics Inc. and Pfizer-BioNTech in 2021 has highlighted...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 35310381
DOI: 10.1016/j.bioactmat.2021.10.018

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