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Evaluating the Clinical Performance of SDC2/NDRG4 Methylation for Colorectal Cancer Detection

1 Jan 2024

Abstract excerpt

Purpose: The performance and clinical accuracy of combined SDC2/NDRG4 methylation were evaluated in diagnosing colorectal cancer (CRC) and advanced adenoma. Methods: A total of 2333 participants were enrolled to assess the sensitivity and specificity of biomarkers in diagnosing CRC in a multicenter clinical trial through feces DNA methylation tests. Results: SDC2/NDRG4 methylation showed excellent performance for...

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PMID: 38226561
DOI: 10.2217/epi-2023-0290

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