Article
Generation of induced pluripotent stem cell line derived from FNAIT patient with CD36 deficiency mutations.
Stem cell research - 1 May 2022
Chen Dawei, Wang Tao, Ye Xin, Xu Xiuzhang, Xia Wenjie, Fu Yongshui
Abstract excerpt
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) caused by anti-CD36 isoantibodies is a common disease and the frequency of type I CD36 deficiency is relatively high in eastern Asian populations.Currently, patient-specific induced pluripotent stem cells (hiPSC) are believed to be useful tools for studying anti-CD36 mediated FNAIT and finding new therapeutic approaches to the disease.We generated an iPSC...
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