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Article

Prenatal psychological or metabolic stress increases the risk for psychiatric disorders: the “funnel effect” model

15 Mar 2022

Abstract excerpt

Adverse stressful experiences in utero can redirect fetal brain development, ultimately leading to increased risk for psychiatric disorders. Obesity during pregnancy can have similar effects as maternal stress, affecting mental health in the offspring. In order to explain how similar outcomes may originate from different prenatal conditions, we propose a "funnel effect" model whereby maternal psychological or...

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PMID: 35304226
DOI: 10.1016/j.neubiorev.2022.104624

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