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Why stem/progenitor cells lose their regenerative potential

23 Nov 2021

Abstract excerpt

epigenomic profile) as well as changes in the tissue microenviroment, both into the niche and by systemic circulating factors. Strikingly, it has been suggested that aging-induced deterioration of stem cell functions may play a key role in the pathophysiology of the various aging-associated disorders. Therefore, understanding how resident stem cell age and affects near and distant tissues is fundamental. Here, we...

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PMID: 34909119
DOI: 10.4252/wjsc.v13.i11.1714

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