Back to search

Article

LINC00520 promotes breast cancer development by low expression as a tumor suppressor and prognostic biomarker by regulating the ESR2 expression level: integrated systems biology bioinformatics and experimental analyses

2022-08-10

Abstract excerpt

<title>Abstract</title> <p>Background <italic>ESR2</italic> can have a remarkable effect on the proliferation and tumorigenesis of breast cancer (BC) as a hub tumor suppressor by regulating the effect of estrogen. The abnormal changes in the expression of the co-expressed lncRNAs can have a regulatory effect on the <italic>ESR2</italic> expression and cause BC status. In this research, the expression and correla...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
77429a9f-f9d5-55a2-aa80-2420aa36b80f
DOI
10.21203/rs.3.rs-1944462/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
LINC00520 promotes breast cancer development by low expression as a tumor suppressor and prognostic biomarker by regulating the ESR2 expression level: integrated systems biology bioinformatics and experimental analysesDOI 10.21203/rs.3.rs-1944462/v1
The dysregulation of NME1, LINC00511, and LINC01028 could disturb the regular apoptosis process and promote breast cancer in the Isfahan population: integrated bioinformatics and experimental analysesSemantic proximity
Clinical Values of two Novel Estrogen Receptor Signaling Targeted lncRNAs in Invasive ductal breast carcinomaSemantic proximity
Development a Prognostic Model Integrating lncRNA/ mRNA novel Biomarkers Identified by Bioinformatics Analysis and Experiments in Breast CancerSemantic proximity
LNC01089-LINC00963/miR-1244-5p/IGF1 ceRNA axis might regulate FOXO signaling pathway in breast cancer patients: a biomarker discovery investigationSemantic proximity
Up-regulation of LINC01010 and lncRNA CASC15 can regulate the p53 signaling pathway and apoptosis process by regulation of PERP expression level as a breast cancer biomarker: Integrated systems biology and experimental approachSemantic proximity
Upregulated CCNE1 Correlates with Poor Prognosis, Tumor Immune Infiltration and Escape in Breast CancerSemantic proximity
An exosome-related long non-coding RNAs risk model could predict survival outcomes in patients with breast cancerSemantic proximity
Down-regulation of ESRP2 inhibits breast cancer cell proliferation via inhibiting cyclinD1Semantic proximity
Transcriptomic insights into the development and therapy of breast cancer via the ncRNA-mediated ceRNA regulation networkSemantic proximity
OCRL is a novel prognostic biomarker and its association with immunoregulation in breast cancerSemantic proximity
lncRNA LINC00652 is a significant prognostic and diagnostic biomarker in the Isfahan Breast cancer patients, correlated to ID1: integrated bioinformatics and experimental approachSemantic proximity
LINC02544 modulates the RAB/RAS signaling pathway by potential regulation of DENND2A expression level in the breast cancer patients: integrated bioinformatics and experimental analysesSemantic proximity
Select a neighboring publication to make it the new centre.