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Article

SARS-CoV-2 Evolution: On the Sudden Appearance of the Omicron Variant.

Journal of virology - 13 Apr 2022

Berkhout Ben, Herrera-Carrillo Elena

Abstract excerpt

The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads rapidly and harbors many mutations in the spike protein, but the origin of this virus variant remains unclear. We address the role of unusual virus evolution mechanisms such as hypermutation, out-of-frame reading, and recombination. Rather, regular Darwinian evolution, that is, the repeated selection of beneficial spike...

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Source

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Identifiers

PMID: 35293771
DOI: 10.1128/jvi.00090-22
PMCID: PMC9006888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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