Article
Potential impact of GCK, MIR-196A-2 and MIR-423 gene abnormalities on the development and progression of type 2 diabetes mellitus in Asir and Tabuk regions of Saudi Arabia.
Molecular medicine reports - 1 May 2022
Mir Mohammad Muzaffar, Mir Rashid, Alghamdi Mushabab Ayed Abdullah, Wani Javed Iqbal, Elfaki Imadeldin, Sabah Zia Ul, Alhujaily Muhanad, Jeelani Mohammed, Marakala Vijaya, Alharthi Muffarah Hamid, Al-Shahrani Abdullah M
Abstract excerpt
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by persistent hyperglycemia and is associated with serious complications. The risk factors for T2DM include both genetic and lifestyle factors. Genome‑wide association studies have indicated the association of genetic variations with many diseases, including T2DM. Glucokinase (GCK) plays a key role in the regulation of insulin release in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.