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Article

Genomic Function of Estrogen Receptor β in Endometriosis

27 Aug 2019

Abstract excerpt

Estrogen receptor (ER) β plays a critical role in endometriosis progression because cytoplasmic ERβ stimulates proinflammatory signaling in ectopic lesions and prevents apoptosis to promote their survival. However, the role of "nuclear ERβ" in endometriosis progression is not known. This critical knowledge gap obscures our understanding of the full molecular etiology of ERβ-mediated endometriosis progression. To...

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Identifiers

PMID: 31504401
DOI: 10.1210/en.2019-00442

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