Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Elevated expression of RAB3B plays important roles in chemoresistance and metastatic potential of hepatoma cells

11 Mar 2022

Abstract excerpt

BACKGROUND: Cancer stem cells (CSCs) are thought to play important roles in carcinogenesis, recurrence, metastasis, and therapy-resistance. We have successfully induced cancer stem-like sphere cells (CSLCs) which possess enhanced chemoresistance and metastatic potential. To enable the development of targeted therapy against CSLCs, we identified a gene responsible for this phenotype in CSLC. METHODS: Human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Extracellular vesicles in disease
Share to FOXO transcription factor regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35277124
DOI: 10.1186/s12885-022-09370-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Elevated expression of RAB3B plays important roles in chemoresistance and metastatic potential of hepatoma cellsPMID 35277124Read ↗

Cancer Stem Cell Functions in Hepatocellular Carcinoma and Comprehensive Therapeutic StrategiesSemantic proximity Read ↗

Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell linesSemantic proximity Read ↗

HBx Facilitates Drug Resistance in Hepatocellular Carcinoma via CD133-regulated Self-renewal of Liver Cancer Stem CellsSemantic proximity Read ↗

Turning Hepatic Cancer Stem Cells Inside Out – A Deeper Understanding through Multiple PerspectivesSemantic proximity Read ↗

Molecular Biology of Liver Cancer Stem CellsSemantic proximity Read ↗

Generation and characterization of hepatocellular carcinoma cell lines with enhanced cancer stem cell potentialSemantic proximity Read ↗

PRC1 and RACGAP1 are Diagnostic Biomarkers of Early HCC and PRC1 Drives Self-Renewal of Liver Cancer Stem CellsSemantic proximity Read ↗

Mechanism of cancer stemness maintenance in human liver cancerSemantic proximity Read ↗

Metastatic human hepatoblastoma cells exhibit enhanced tumorigenicity, invasiveness and a stem cell-like phenotype.Semantic proximity Read ↗

A Novel lncRNA-Mediated Signaling Axis Governs Cancer Stemness and Splicing Reprogramming in Hepatocellular Carcinoma with Therapeutic PotentialSemantic proximity Read ↗

RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion.Semantic proximity Read ↗

BCL11B suppresses tumor progression and stem cell traits in hepatocellular carcinoma by restoring p53 signaling activitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.