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Single-Cell Transcriptome Comparison of Bladder Cancer Reveals Its Ecosystem

21 Feb 2022

Abstract excerpt

Bladder carcinoma (BLCA) is a highly heterogeneous disease, and the underlying biological behavior is still poorly understood. Here, single-cell RNA sequencing was performed on four clinical samples of different grades from three patients, and 26,792 cell transcriptomes were obtained revealing different tumor ecosystems. We found that N-glycan biosynthesis pathway was activated in high-grade tumor, but...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 35265520
DOI: 10.3389/fonc.2022.818147

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