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Insidious Insights: Implications of viral vector engineering for pathogen enhancement

10 Mar 2022

Abstract excerpt

Optimizing viral vectors and their properties will be important for improving the effectiveness and safety of clinical gene therapy. However, such research may generate dual-use insights relevant to the enhancement of pandemic pathogens. In particular, reliable and generalizable methods of immune evasion could increase viral fitness sufficient to cause a new pandemic. High potential for misuse is associated with...

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PMID: 35264741
DOI: 10.1038/s41434-021-00312-3

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