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Article

Common genetic variants do not predict recurrent events in coronary heart disease patients.

BMC cardiovascular disorders - 9 Mar 2022

Thompson P L, Hui J, Beilby J, Palmer L J, Watts G F, West M J, Kirby A, Marschner S, Simes R J, Sullivan D R, White H D, Stewart R, Tonkin A M

Abstract excerpt

BACKGROUND: It is unclear whether genetic variants identified from single nucleotide polymorphisms (SNPs) strongly associated with coronary heart disease (CHD) in genome-wide association studies (GWAS), or a genetic risk score (GRS) derived from them, can help stratify risk of recurrent events in patients with CHD. METHODS: Study subjects were enrolled at the close-out of the LIPID randomised controlled trial of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35264114
DOI: 10.1186/s12872-022-02520-0
PMCID: PMC8908687

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