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Article

CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts.

Oxidative medicine and cellular longevity - 1 Jan 2022

Chen Yu-Hsiu, Zhang Xin, Ko Kuei-Yueh, Hsueh Ming-Feng, Kraus Virginia Byers

Abstract excerpt

Cellular senescence is characterized by cell cycle arrest and senescence-associated secretory phenotypes. Cellular senescence can be caused by various stress stimuli such as DNA damage, oxidative stress, and telomere attrition and is related to several chronic diseases, including atherosclerosis, Alzheimer's disease, and osteoarthritis. Chromobox homolog 4 (CBX4) has been shown to alleviate cellular senescence in...

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Identifiers

PMID: 35251476
DOI: 10.1155/2022/5503575
PMCID: PMC8890863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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