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Article

Psorachromene induces apoptosis and suppresses tumor growth in NSCLC cells harboring EGFR L858R/T790M/C797S.

Phytotherapy research : PTR - 1 May 2022

Wang Tong-Hong, Leu Yann-Lii, Chen Chin-Chuan, Li Hsin-Jung, Yang Shuenn-Chen, Huang Kuo-Yen, Chen Chi-Yuan

Abstract excerpt

The extracts from Psoralea corylifolia Linn. (P. corylifolia) seeds have been shown to display antitumor activity. To date, the prospects of this plant and its active compounds in the treatment of non-small-cell lung cancer (NSCLC) have not been thoroughly studied. In this study, we identified a novel psorachromene compound that displays selective cytotoxic effects on all NSCLC cells tested, including NSCLC cells...

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PMID: 35229911
DOI: 10.1002/ptr.7432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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