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Article

Targeting Diagnosis of High-Risk Papillary Thyroid Carcinoma Using Ultrasound Contrast Agent With the BRAFV600E Mutation: An Experimental Study.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine - 1 Nov 2022

Xie Fang, Yan Lin, Li Yi-Ming, Lan Yu, Xiao Jing, Zhang Ming-Bo, Jin Zhuang, Zhang Ying, Tian Xiao-Qi, Zhu Ya-Qiong, Li Zhi-Ping, Luo Yu-Kun

Abstract excerpt

OBJECTIVE: High-risk papillary thyroid carcinoma (PTC) patients with BRAF mutation have lymph node and distant metastases and poor prognosis. Therefore, this study aims to develop a targeted ultrasound contrast agent for the BRAFV600E mutation to screen high-risk PTC at early stage. METHODS: The targeted lipid nanobubbles carrying BRAFV600E antibody were prepared using thin film hydration-sonication and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 35229905
DOI: 10.1002/jum.15967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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